Ändringar

View changes from to

6 december 2023 07.57.46 +0800, Albert Yang:

Ändrade titel till Dementia Molecular Imaging Clinical Database at Taipei Veterans General Hospital (tidigare 台北榮總失智症分子影像臨床資料庫)

Ändrade förvaltare av Dementia Molecular Imaging Clinical Database at Taipei Veterans General Hospital till Jung-Ling Fuh, MD (tidigare 傅中玲主任)

Uppdaterade beskrivningen av Dementia Molecular Imaging Clinical Database at Taipei Veterans General Hospital från
腦神經受損後，局部腦血流與其代謝功能皆會受到影響。腦部斷層灌注掃描(single-photon emission computed tomography, SPECT)及葡萄糖正子攝影(fluorodeoxyglucose positron emission tomography, FDG-PET) 這兩種分子影像(molecular imaging)都是目前臨床上失智症診斷的利器。經由解析病患腦血流及葡萄糖代謝圖譜，發現兩者間的相關性非常高。因此本研究欲透過 SPECT 與其對應的臨床認知功能常模並採用 AI 運算方式，以結構性腦影像 MRI 來預測腦部葡萄糖代謝功能分子影像，即 zero-dose FDG-PET，協助早期診斷出失智症高危險者，在減少輻射暴露的同時亦可降低醫療支出，並解決正子攝影的普及率遠較磁振造影低的現況。
till
Dementia involves both changes in local cerebral blood flow and metabolic function. Two types of molecular imaging, single-photon emission computed tomography (SPECT) and fluorodeoxyglucose positron emission tomography (FDG-PET), are currently powerful tools in the clinical diagnosis of dementia. By analyzing the patterns of cerebral blood flow and glucose metabolism, a high correlation between them has been found. Therefore, this study aims to use SPECT and its corresponding clinical cognitive function norms, employing AI computation, to predict cerebral glucose metabolic function molecular imaging using structural brain imaging MRI, i.e., zero-dose FDG-PET. This assists in the early diagnosis of individuals at high risk of dementia while reducing radiation exposure and medical expenses. It also addresses the current situation where the prevalence of positron emission imaging is much lower than magnetic resonance imaging.

Lade till följande taggar till Dementia Molecular Imaging Clinical Database at Taipei Veterans General Hospital
- brain
- brain image

Ändrade licens för Dementia Molecular Imaging Clinical Database at Taipei Veterans General Hospital till Creative Commons Attribution (tidigare )

              
    
          
          
        
        
            f 1 { f 1 {
            2   "author": "", 2   "author": "",
            3   "author_email": "", 3   "author_email": "",
            4   "creator_user_id": "d0933fa5-81eb-4fe8-ab8b-d30d9c12d8e7", 4   "creator_user_id": "d0933fa5-81eb-4fe8-ab8b-d30d9c12d8e7",
            5   "extras": [], 5   "extras": [],
            n 6   "groups": [], n 6   "groups": [
            7     {
            8       "description": "",
            9       "display_name": "Brain Image",
            10       "id": "9765d9ee-aa92-4df1-a4e8-449093b96e9d",
            11       "image_display_url": 
            12 ps://data.dmc.nycu.edu.tw/uploads/group/2022-05-20-061942.864108.png",
            13       "name": "brain-image",
            14       "title": "Brain Image"
            15     }
            16   ],
            7   "id": "33dfd77a-7a35-4950-9847-3db3f9e4e954", 17   "id": "33dfd77a-7a35-4950-9847-3db3f9e4e954",
            n 8   "isopen": false, n 18   "isopen": true,
            9   "license_id": "", 19   "license_id": "cc-by",
            10   "license_title": "", 20   "license_title": "Creative Commons Attribution",
            11   "maintainer": "\u5085\u4e2d\u73b2\u4e3b\u4efb", 21   "license_url": "http://www.opendefinition.org/licenses/cc-by",
            22   "maintainer": "Jung-Ling Fuh, MD",
            12   "maintainer_email": "stellafuh@gmail.com", 23   "maintainer_email": "stellafuh@gmail.com",
            13   "metadata_created": "2022-11-02T11:44:22.263119", 24   "metadata_created": "2022-11-02T11:44:22.263119",
            n 14   "metadata_modified": "2022-11-03T01:54:38.088316", n 25   "metadata_modified": "2023-12-05T23:57:46.242271",
            15   "name": "dementia_spect", 26   "name": "dementia_spect",
            n 16   "notes":  n 27   "notes": "Dementia involves both changes in local cerebral blood 
            17 ff\u3002\u8166\u90e8\u65b7\u5c64\u704c\u6ce8\u6383\u63cf(single-photon  28 flow and metabolic function. Two types of molecular imaging, 
            18 emission computed tomography,  29 single-photon emission computed tomography (SPECT) and 
            19 CT)\u53ca\u8461\u8404\u7cd6\u6b63\u5b50\u651d\u5f71(fluorodeoxyglucose  30 fluorodeoxyglucose positron emission tomography (FDG-PET), are 
            20 positron emission tomography, FDG-PET)  31 currently powerful tools in the clinical diagnosis of dementia. By 
            21 \u9019\u5169\u7a2e\u5206\u5b50\u5f71\u50cf(molecular  32 analyzing the patterns of cerebral blood flow and glucose metabolism, 
            22 975e\u5e38\u9ad8\u3002\u56e0\u6b64\u672c\u7814\u7a76\u6b32\u900f\u904e  33 a high correlation between them has been found. Therefore, this study 
            23 SPECT  34 aims to use SPECT and its corresponding clinical cognitive function 
            24 7684\u81e8\u5e8a\u8a8d\u77e5\u529f\u80fd\u5e38\u6a21\u4e26\u63a1\u7528  35 norms, employing AI computation, to predict cerebral glucose metabolic 
            25 AI  36 function molecular imaging using structural brain imaging MRI, i.e., 
            26 904b\u7b97\u65b9\u5f0f\uff0c\u4ee5\u7d50\u69cb\u6027\u8166\u5f71\u50cf  37 zero-dose FDG-PET. This assists in the early diagnosis of individuals 
            27 MRI  38 at high risk of dementia while reducing radiation exposure and medical 
            28 8404\u7cd6\u4ee3\u8b1d\u529f\u80fd\u5206\u5b50\u5f71\u50cf\uff0c\u5373  39 expenses. It also addresses the current situation where the prevalence 
            29 zero-dose  40 of positron emission imaging is much lower than magnetic resonance 
            30 5371\u96aa\u8005\uff0c\u5728\u6e1b\u5c11\u8f3b\u5c04\u66b4\u9732\u7684  41 imaging.",
            31 87\u9060\u8f03\u78c1\u632f\u9020\u5f71\u4f4e\u7684\u73fe\u6cc1\u3002", 
            32   "num_resources": 4, 42   "num_resources": 4,
            n 33   "num_tags": 2, n 43   "num_tags": 4,
            34   "organization": { 44   "organization": {
            35     "approval_status": "approved", 45     "approval_status": "approved",
            36     "created": "2022-05-20T15:43:19.080718", 46     "created": "2022-05-20T15:43:19.080718",
            37     "description": "", 47     "description": "",
            38     "id": "25188a0c-7f13-4562-a5e2-042df726de3c", 48     "id": "25188a0c-7f13-4562-a5e2-042df726de3c",
            39     "image_url": "2022-05-20-074319.065617vghtpelogo.png", 49     "image_url": "2022-05-20-074319.065617vghtpelogo.png",
            40     "is_organization": true, 50     "is_organization": true,
            41     "name": "taipei-veterans-general-hospital", 51     "name": "taipei-veterans-general-hospital",
            42     "state": "active", 52     "state": "active",
            43     "title": "Taipei Veterans General Hospital", 53     "title": "Taipei Veterans General Hospital",
            44     "type": "organization" 54     "type": "organization"
            45   }, 55   },
            46   "owner_org": "25188a0c-7f13-4562-a5e2-042df726de3c", 56   "owner_org": "25188a0c-7f13-4562-a5e2-042df726de3c",
            47   "private": false, 57   "private": false,
            48   "relationships_as_object": [], 58   "relationships_as_object": [],
            49   "relationships_as_subject": [], 59   "relationships_as_subject": [],
            50   "resources": [ 60   "resources": [
            51     { 61     {
            52       "cache_last_updated": null, 62       "cache_last_updated": null,
            53       "cache_url": null, 63       "cache_url": null,
            54       "created": "2022-11-02T11:44:54.808317", 64       "created": "2022-11-02T11:44:54.808317",
            55       "datastore_active": false, 65       "datastore_active": false,
            56       "description": "", 66       "description": "",
            57       "format": "PDF", 67       "format": "PDF",
            58       "hash": "", 68       "hash": "",
            59       "id": "e4ddc30e-b0c8-4197-9cc7-5bc557881d89", 69       "id": "e4ddc30e-b0c8-4197-9cc7-5bc557881d89",
            60       "last_modified": "2022-11-02T11:44:54.760809", 70       "last_modified": "2022-11-02T11:44:54.760809",
            61       "metadata_modified": "2022-11-02T11:52:28.025850", 71       "metadata_modified": "2022-11-02T11:52:28.025850",
            62       "mimetype": "application/pdf", 72       "mimetype": "application/pdf",
            63       "mimetype_inner": null, 73       "mimetype_inner": null,
            64       "name":  74       "name": 
            65 "\u8cc7\u6599\u96c6\u8aaa\u660e\u6587\u4ef6\u6307\u5f15_v1.2.pdf", 75 "\u8cc7\u6599\u96c6\u8aaa\u660e\u6587\u4ef6\u6307\u5f15_v1.2.pdf",
            66       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954", 76       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954",
            67       "position": 0, 77       "position": 0,
            68       "resource_type": null, 78       "resource_type": null,
            69       "size": 486520, 79       "size": 486520,
            70       "state": "active", 80       "state": "active",
            71       "url":  81       "url": 
            72 954/resource/e4ddc30e-b0c8-4197-9cc7-5bc557881d89/download/_v1.2.pdf", 82 954/resource/e4ddc30e-b0c8-4197-9cc7-5bc557881d89/download/_v1.2.pdf",
            73       "url_type": "upload" 83       "url_type": "upload"
            74     }, 84     },
            75     { 85     {
            76       "cache_last_updated": null, 86       "cache_last_updated": null,
            77       "cache_url": null, 87       "cache_url": null,
            78       "created": "2022-11-02T11:52:28.048321", 88       "created": "2022-11-02T11:52:28.048321",
            79       "datastore_active": false, 89       "datastore_active": false,
            80       "description": "MCI", 90       "description": "MCI",
            81       "format": "", 91       "format": "",
            82       "hash": "", 92       "hash": "",
            83       "id": "87645dfc-ab13-47c5-ab0e-1d4d34fc41be", 93       "id": "87645dfc-ab13-47c5-ab0e-1d4d34fc41be",
            84       "last_modified": "2022-11-02T11:52:28.001732", 94       "last_modified": "2022-11-02T11:52:28.001732",
            85       "metadata_modified": "2022-11-02T11:52:38.569446", 95       "metadata_modified": "2022-11-02T11:52:38.569446",
            86       "mimetype": null, 96       "mimetype": null,
            87       "mimetype_inner": null, 97       "mimetype_inner": null,
            88       "name": "ECD_SEPCT_M001.nii", 98       "name": "ECD_SEPCT_M001.nii",
            89       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954", 99       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954",
            90       "position": 1, 100       "position": 1,
            91       "resource_type": null, 101       "resource_type": null,
            92       "size": 4246242, 102       "size": 4246242,
            93       "state": "active", 103       "state": "active",
            94       "url":  104       "url": 
            95 rce/87645dfc-ab13-47c5-ab0e-1d4d34fc41be/download/ecd_sepct_m001.nii", 105 rce/87645dfc-ab13-47c5-ab0e-1d4d34fc41be/download/ecd_sepct_m001.nii",
            96       "url_type": "upload" 106       "url_type": "upload"
            97     }, 107     },
            98     { 108     {
            99       "cache_last_updated": null, 109       "cache_last_updated": null,
            100       "cache_url": null, 110       "cache_url": null,
            101       "created": "2022-11-02T11:52:38.580979", 111       "created": "2022-11-02T11:52:38.580979",
            102       "datastore_active": false, 112       "datastore_active": false,
            103       "description": "MCI", 113       "description": "MCI",
            104       "format": "", 114       "format": "",
            105       "hash": "", 115       "hash": "",
            106       "id": "76840176-92ac-4208-bd99-1434e9881380", 116       "id": "76840176-92ac-4208-bd99-1434e9881380",
            107       "last_modified": "2022-11-02T11:52:38.556184", 117       "last_modified": "2022-11-02T11:52:38.556184",
            108       "metadata_modified": "2022-11-02T11:52:51.579204", 118       "metadata_modified": "2022-11-02T11:52:51.579204",
            109       "mimetype": null, 119       "mimetype": null,
            110       "mimetype_inner": null, 120       "mimetype_inner": null,
            111       "name": "ECD_SEPCT_M002.nii", 121       "name": "ECD_SEPCT_M002.nii",
            112       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954", 122       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954",
            113       "position": 2, 123       "position": 2,
            114       "resource_type": null, 124       "resource_type": null,
            115       "size": 4246242, 125       "size": 4246242,
            116       "state": "active", 126       "state": "active",
            117       "url":  127       "url": 
            118 rce/76840176-92ac-4208-bd99-1434e9881380/download/ecd_sepct_m002.nii", 128 rce/76840176-92ac-4208-bd99-1434e9881380/download/ecd_sepct_m002.nii",
            119       "url_type": "upload" 129       "url_type": "upload"
            120     }, 130     },
            121     { 131     {
            122       "cache_last_updated": null, 132       "cache_last_updated": null,
            123       "cache_url": null, 133       "cache_url": null,
            124       "created": "2022-11-02T11:52:51.590530", 134       "created": "2022-11-02T11:52:51.590530",
            125       "datastore_active": false, 135       "datastore_active": false,
            126       "description": "MCI", 136       "description": "MCI",
            127       "format": "", 137       "format": "",
            128       "hash": "", 138       "hash": "",
            129       "id": "0896b05f-0dab-483d-b151-6839dd662026", 139       "id": "0896b05f-0dab-483d-b151-6839dd662026",
            130       "last_modified": "2022-11-02T11:52:51.565845", 140       "last_modified": "2022-11-02T11:52:51.565845",
            131       "metadata_modified": "2022-11-02T11:52:52.285291", 141       "metadata_modified": "2022-11-02T11:52:52.285291",
            132       "mimetype": null, 142       "mimetype": null,
            133       "mimetype_inner": null, 143       "mimetype_inner": null,
            134       "name": "ECD_SEPCT_M003.nii", 144       "name": "ECD_SEPCT_M003.nii",
            135       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954", 145       "package_id": "33dfd77a-7a35-4950-9847-3db3f9e4e954",
            136       "position": 3, 146       "position": 3,
            137       "resource_type": null, 147       "resource_type": null,
            138       "size": 4246242, 148       "size": 4246242,
            139       "state": "active", 149       "state": "active",
            140       "url":  150       "url": 
            141 rce/0896b05f-0dab-483d-b151-6839dd662026/download/ecd_sepct_m003.nii", 151 rce/0896b05f-0dab-483d-b151-6839dd662026/download/ecd_sepct_m003.nii",
            142       "url_type": "upload" 152       "url_type": "upload"
            143     } 153     }
            144   ], 154   ],
            145   "state": "active", 155   "state": "active",
            146   "tags": [ 156   "tags": [
            147     { 157     {
            148       "display_name": "Dementia", 158       "display_name": "Dementia",
            149       "id": "bf63aa0c-0c9e-468b-ad3c-2ef4e1470362", 159       "id": "bf63aa0c-0c9e-468b-ad3c-2ef4e1470362",
            150       "name": "Dementia", 160       "name": "Dementia",
            151       "state": "active", 161       "state": "active",
            152       "vocabulary_id": null 162       "vocabulary_id": null
            153     }, 163     },
            154     { 164     {
            155       "display_name": "SPECT", 165       "display_name": "SPECT",
            156       "id": "f2a31af2-619a-42d3-936c-985f49afa4d2", 166       "id": "f2a31af2-619a-42d3-936c-985f49afa4d2",
            157       "name": "SPECT", 167       "name": "SPECT",
            158       "state": "active", 168       "state": "active",
            159       "vocabulary_id": null 169       "vocabulary_id": null
            n n 170     },
            171     {
            172       "display_name": "brain",
            173       "id": "7828821f-c0ef-4377-98c3-4261eee91cf1",
            174       "name": "brain",
            175       "state": "active",
            176       "vocabulary_id": null
            177     },
            178     {
            179       "display_name": "brain image",
            180       "id": "e6e4b86c-3c9b-43a8-9482-f9d6818cbd5d",
            181       "name": "brain image",
            182       "state": "active",
            183       "vocabulary_id": null
            160     } 184     }
            161   ], 185   ],
            t 162   "title":  t 186   "title": "Dementia Molecular Imaging Clinical Database at Taipei 
            163 31\u667a\u75c7\u5206\u5b50\u5f71\u50cf\u81e8\u5e8a\u8cc7\u6599\u5eab", 187 Veterans General Hospital",
            164   "type": "dataset", 188   "type": "dataset",
            165   "url": "", 189   "url": "",
            166   "version": "" 190   "version": ""
            167 } 191 }